Table 3 Functional enrichment of AA genes in clusters. Functional enrichment analysis was performed for cluster annotation using DEVID bioinformatics resource, exploring the well known database: Gene Ontology (GO) database. We especially annotated the clusters with GO BP (Biological Process), MF (Molecular Function) and CC (Cellular Component) terms
| #Cluster | Gene size | GO | Term ID | Description | Count | P a values* |
|---|---|---|---|---|---|---|
| 1 | 79 | BP | GO:0022402 | cell cycle process | 35 | 6.76E-26 |
| GO:0000278 | mitotic cell cycle | 26 | 4.09E-19 | |||
| GO:0006281 | DNA repair | 12 | 1.13E-04 | |||
| GO:0051327 | M phase of meiotic cell cycle | 7 | 0.006 | |||
| GO:0051437 |
positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle | 6 | 0.014 | |||
| MF | GO:0005524 | ATP binding | 22 | 3.86E-05 | ||
| CC | GO:0031981 | nuclear lumen | 27 | 1.20E-08 | ||
| GO:0015630 | microtubule cytoskeleton | 19 | 1.60E-09 | |||
| 2 | 22 | MF | GO:0005200 | structural constituent of cytoskeleton | 4 | 0.008 |
| GO:0005198 | structural molecule activity | 7 | 0.009 | |||
| CC | GO:0030057 | desmosome | 3 | 0.018 | ||
| 3 | 5 | MF | GO:0005509 | calcium ion binding | 5 | 4.99E-04 |